Force-induced breakdown of flexible polymerized membrane

Molecular mechanism of force induced stabilization of collagen against enzymatic breakdown Citation

Collagen cleavage, facilitated by collagenases of the matrix metalloproteinase (MMP) family, is crucial for many physiological and pathological processes such as wound healing, tissue remodeling, cancer invasion and organ morphogenesis. Earlier work has shown that mechanical force alters the cleavage rate of collagen. However, experimental results yielded conflicting data on whether applying fo...

Molecular mechanism of force induced stabilization of collagen against enzymatic breakdown.

Collagen cleavage, facilitated by collagenases of the matrix metalloproteinase (MMP) family, is crucial for many physiological and pathological processes such as wound healing, tissue remodeling, cancer invasion and organ morphogenesis. Earlier work has shown that mechanical force alters the cleavage rate of collagen. However, experimental results yielded conflicting data on whether applying fo...

Protein-induced membrane curvature investigated through molecular dynamics flexible fitting.

In the photosynthetic purple bacterium Rhodobacter (Rba.) sphaeroides, light is absorbed by membrane-bound light-harvesting (LH) proteins LH1 and LH2. LH1 directly surrounds the reaction center (RC) and, together with PufX, forms a dimeric (RC-LH1-PufX)2 protein complex. In LH2-deficient Rba. sphaeroides mutants, RC-LH1-PufX dimers aggregate into tubular vesicles with a radius of approximately ...

The effect of support parameters on the force transmissibility of a flexible rotor

Rotating machinery support design with the aim of reducing the force transmitted to the foundation has significant importance regarding the various applications of these machineries. In this paper presents a rapid approximate method for calculating the optimum support flexibility and damping of flexible rotors to minimize force transmissibility in the vicinity of the rotor first critical speed....

Laser-Induced Breakdown Spectroscopy